Annotation-Informed Block-Sparse Bayesian Modeling for cis-Expression Prediction

Genotype-based cis-expression prediction depends on accurately modeling local regulatory architecture. We present block-sparse Bayesian sparse linear mixed model (bsBSLMM), an extension of Bayesian sparse linear mixed model (BSLMM) that incorporates linkage disequilibrium (LD)-block spike-and-slab sparsity and a transcription start site (TSS)-informed SNP inclusion prior. Across 23,098 genes from GEUVADIS European-ancestry lymphoblastoid cell lines, bsBSLMM retained more predictable genes than BSLMM, LASSO, BLUP, TIGAR elastic net, and TIGAR Dirichlet-process regression under matched evaluation criteria. Compared with BSLMM, bsBSLMM improved held-out prediction performance for most shared genes, with gains driven primarily by LD-block sparsity and further enhanced by the TSS-informed prior. Variants selected by bsBSLMM showed stronger enrichment in GM12878 DNase and H3K27ac regulatory regions than variants selected by BSLMM. In transcriptome-wide association study (TWAS) analysis, bsBSLMM recovered established inflammatory bowel disease signals, including IL23R, and identified additional genome-wide significant genes not detected by BSLMM. Independent validation in the Louisiana Osteoporosis Study reproduced the increased prediction yield across ancestries and recovered biologically relevant bone mineral density pathways in downstream TWAS and gene set enrichment analyses. These results demonstrate that incorporating LD-block structure and biologically informed SNP priors improves cis-expression prediction and enhances downstream TWAS discovery.

Agentic Recommender System with Hierarchical Belief-State Memory

Memory-augmented LLM agents have advanced personalized recommendation, yet existing approaches universally adopt flat memory representations that conflate ephemeral signals with stable preferences, and none provides a complete lifecycle governing how memory should evolve. We propose MARS (Memory-Augmented Agentic Recommender System), a framework that treats recommendation as a partially observable problem and maintains a structured belief state that progressively abstracts noisy behavioral observations into a compact estimate of user preferences. MARS organizes this belief state into three tiers: event memory buffers raw signals, preference memory maintains fine-grained mutable chunks with explicit strength and evidence tracking, and profile memory distills all preferences into a coherent natural language narrative. A complete lifecycle of six operations -- extraction, reinforcement, weakening, consolidation, forgetting, and resynthesis -- is adaptively scheduled by an LLM-based planner rather than fixed-interval heuristics. Experiments on four InstructRec benchmark domains show that \ours achieves state-of-the-art performance with average improvements of 26.4% in HR@1 and 10.3% in NDCG@10 over the strongest baselines with further gains from agentic scheduling in evolving settings.

Enjoy Your Layer Normalization with the Computational Efficiency of RMSNorm

Layer normalization (LN) is a fundamental component in modern deep learning, but its per-sample centering and scaling introduce non-negligible inference overhead. RMSNorm improves efficiency by removing the centering operation, yet this may discard benefits associated with centering. This paper propose a framework to determine whether an LN in an arbitrary DNN can be replaced by RMSNorm without changing the model function. The key idea is to fold LN's centering operation into upstream general linear layers by enforcing zero-mean outputs through the column-centered constraint (CCC) and column-based weight centering (CBWC). We extend the analysis to arbitrary DNNs, define such LNs as foldable LNs, and develop a graph-based detection algorithm. Our analysis shows that many LNs in widely used architectures are foldable, enabling exact inference-time conversion and end-to-end acceleration of 2% to 12% without changing model predictions. Experiments across multiple task families further show that, when exact equivalence is partially broken in practical training settings, our method remains competitive with vanilla LN while improving efficiency.

Anti-Self-Distillation for Reasoning RL via Pointwise Mutual Information

On-policy self-distillation, where a student is pulled toward a copy of itself conditioned on privileged context (e.g., a verified solution or feedback), offers a promising direction for advancing reasoning capability without a stronger external teacher. Yet in math reasoning the gains are inconsistent, even when the same approach succeeds elsewhere. A pointwise mutual information analysis traces the failure to the privileged context itself: it inflates the teacher's confidence on tokens already implied by the solution (structural connectives, verifiable claims) and deflates it on deliberation tokens ("Wait", "Let", "Maybe") that drive multi-step search. We propose Anti-Self-Distillation (AntiSD), which ascends a divergence between student and teacher rather than descending it: this reverses the per-token sign and yields a naturally bounded advantage in one step. An entropy-triggered gate disables the term once the teacher entropy collapses, completing a drop-in replacement for default self-distillation. Across five models from 4B to 30B parameters on math reasoning benchmarks, AntiSD reaches the GRPO baseline's accuracy in 2 to 10x fewer training steps and improves final accuracy by up to 11.5 points. AntiSD opens a path to scalable self-improvement, where a language model bootstraps its own reasoning through its training signal.

From Generic Correlation to Input-Specific Credit in On-Policy Self Distillation

On-policy self-distillation has emerged as a promising paradigm for post-training language models, in which the model conditions on environment feedback to serve as its own teacher, providing dense token-level rewards without external teacher models or step-level annotations. Despite its empirical success, what this reward actually measures and what kind of credit it assigns remain unclear. Under a posterior-compatibility interpretation of feedback conditioning, standard in the implicit-reward literature, we show that the self-distillation token reward is a Bayesian filtering increment whose trajectory sum is exactly the pointwise mutual information between the response and the feedback given the input. This pMI can be raised by input-specific reasoning or by input-generic shortcuts, so we further decompose the teacher log-probability along the input axis. Based on this analysis, we propose CREDIT (Contrastive REward from DIsTillation), which isolates the input-specific component with a batch-contrastive baseline. At the sequence level, CREDIT is a teacher-side surrogate for a contrastive pMI objective that also penalizes responses remaining likely under unrelated inputs. Across coding, scientific reasoning, and tool-use benchmarks on two model families, CREDIT delivers the strongest aggregate performance at negligible additional compute.

CAST: Mitigating Object Hallucination in Large Vision-Language Models via Caption-Guided Visual Attention Steering

Although Large Vision-Language Models (LVLMs) have demonstrated remarkable performance on downstream tasks, they frequently produce contents that deviate from visual information, leading to object hallucination. To tackle this, recent works mostly depend on expensive manual annotations and training cost, or decoding strategies which significantly increase inference time. In this work, we observe that LVLMs' attention to visual information is significantly enhanced when answering caption queries compared to non-caption queries. Inspired by this phenomenon, we propose Caption-guided Visual Attention Steering (CAST), a training-free, plug-and-play hallucination mitigation method that leverages the attention activation pattern corresponding to caption queries to enhance LVLMs' visual perception capability. Specifically, we use probing techniques to identify attention heads that are highly sensitive to caption queries and estimate optimized steering directions for their outputs. This steering strengthens LVLM's fine-grained visual perception capabilities, thereby effectively mitigating object hallucination. CAST reduced object hallucination by an average of 6.03% across five widely used LVLMs and five benchmarks including both discriminative and generative tasks, demonstrating state-of-the-art performance while adding little inference cost and preserving other foundational capabilities.

SAVOIR: Learning Social Savoir-Faire via Shapley-based Reward Attribution

Social intelligence, the ability to navigate complex interpersonal interactions, presents a fundamental challenge for language agents. Training such agents via reinforcement learning requires solving the credit assignment problem: determining how individual utterances contribute to multi-turn dialogue outcomes. Existing approaches directly employ language models to distribute episode-level rewards, yielding attributions that are retrospective and lack theoretical grounding. We propose SAVOIR (ShApley Value fOr SocIal RL), a novel principled framework grounded in cooperative game theory. Our approach combines two complementary principles: expected utility shifts evaluation from retrospective attribution to prospective valuation, capturing an utterance's strategic potential for enabling favorable future trajectories; Shapley values ensure fair credit distribution with axiomatic guarantees of efficiency, symmetry, and marginality. Experiments on the SOTOPIA benchmark demonstrate that SAVOIR achieves new state-of-the-art performance across all evaluation settings, with our 7B model matching or exceeding proprietary models including GPT-4o and Claude-3.5-Sonnet. Notably, even large reasoning models consistently underperform, suggesting social intelligence requires qualitatively different capabilities than analytical reasoning.

Stratagem: Learning Transferable Reasoning via Trajectory-Modulated Game Self-Play

Games offer a compelling paradigm for developing general reasoning capabilities in language models, as they naturally demand strategic planning, probabilistic inference, and adaptive decision-making. However, existing self-play approaches rely solely on terminal game outcomes, providing no mechanism to distinguish transferable reasoning patterns from game-specific heuristics. We present STRATAGEM, which addresses two fundamental barriers to reasoning transfer: domain specificity, where learned patterns remain anchored in game semantics, and contextual stasis, where static game contexts fail to cultivate progressive reasoning. STRATAGEM selectively reinforces trajectories exhibiting abstract, domain-agnostic reasoning through a Reasoning Transferability Coefficient, while incentivizing adaptive reasoning development via a Reasoning Evolution Reward. Experiments across mathematical reasoning, general reasoning, and code generation benchmarks demonstrate substantial improvements, with particularly strong gains on competition-level mathematics where multi-step reasoning is critical. Ablation studies and human evaluation confirm that both components contribute to transferable reasoning.

Mutual Coupling-Aware Beamforming in Multi-User Continuous Aperture Array Systems

A mutual coupling-aware beamforming design for continuous aperture array (CAPA)-aided multi-user systems is investigated. First, a transmit coupling kernel is characterized to explicitly capture the mutual coupling effects inherent in CAPAs, based on which a mutual coupling-aware sum-rate maximization functional optimization problem is formulated. To address this problem, a kernel approximation (KA)-based weighted minimum mean-squared error (WMMSE) algorithm is developed. The optimal beamforming condition is derived within the WMMSE framework using the calculus of variations, while KA is employed to obtain a closed-form beamforming solution via wavenumber-domain Fourier transforms and Gauss-Legendre quadrature. Furthermore, the proposed framework is extended to CAPA-to-CAPA multiple-input multiple-output (MIMO) systems. Finally, numerical results demonstrate that: 1) the proposed algorithm achieves improved performance compared to benchmark schemes; 2) the modeled coupling effects are physically rational, where the performance of spatially discrete arrays converges to that of CAPAs; and 3) CAPA-to-CAPA MIMO systems can achieve higher degrees of freedom when the transceivers are placed in close proximity.

SFFNet: Synergistic Feature Fusion Network With Dual-Domain Edge Enhancement for UAV Image Object Detection

Object detection in unmanned aerial vehicle (UAV) images remains a highly challenging task, primarily caused by the complexity of background noise and the imbalance of target scales. Traditional methods easily struggle to effectively separate objects from intricate backgrounds and fail to fully leverage the rich multi-scale information contained within images. To address these issues, we have developed a synergistic feature fusion network (SFFNet) with dual-domain edge enhancement specifically tailored for object detection in UAV images. Firstly, the multi-scale dynamic dual-domain coupling (MDDC) module is designed. This component introduces a dual-driven edge extraction architecture that operates in both the frequency and spatial domains, enabling effective decoupling of multi-scale object edges from background noise. Secondly, to further enhance the representation capability of the model's neck in terms of both geometric and semantic information, a synergistic feature pyramid network (SFPN) is proposed. SFPN leverages linear deformable convolutions to adaptively capture irregular object shapes and establishes long-range contextual associations around targets through the designed wide-area perception module (WPM). Moreover, to adapt to the various applications or resource-constrained scenarios, six detectors of different scales (N/S/M/B/L/X) are designed. Experiments on two challenging aerial datasets (VisDrone and UAVDT) demonstrate the outstanding performance of SFFNet-X, achieving 36.8 AP and 20.6 AP, respectively. The lightweight models (N/S) also maintain a balance between detection accuracy and parameter efficiency. The code will be available at https://github.com/CQNU-ZhangLab/SFFNet.